The Pez-TGFbeta-miR200-ZEB1-2 axis in breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/626918

Funding Status
Closed

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Funded Activity Summary

A feature of late-stage cancer is metastasis - the dissemination of cancer cells to other tissues. Despite advances in treatment of primary cancers, metastatic disease remains the major cause of death in cancer patients. In metastatic cancers, the cells undergo a change that enables them to initially invade the surrounding tissues. We have discovered a novel regulator of the invasive process in tissue culture and this study aims to substantiate its role in breast cancer.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $533,541.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | cancer: mechanisms of growth, invasion, metastasis | cell signalling | metastases | molecular basis of disease | protein tyrosine phosphatase | signalling pathways | transforming growth factor

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