Understanding the mechanisms of substrate and ubiquitin lysine specificity during ubiquitination

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/620205

Funding Status
Closed

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Funded Activity Summary

Ubiquitin is a small molecule which controls all facets of a cell's growth and biology, such as growth. Ubiquitin functions by being attached to proteins in cells to alter their function and hence a particular chemical pathway. How ubiquitin is attached to proteins is poorly understood. This studiy will unveil how enzymes termed Ubcs attach ubiquitin to proteins, which is fundamental to understanding how ubiquitn controls cell functions.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $573,993.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | cancer biology | cell cycle | multiple myeloma | proteasome | ubiquitin

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