ROLE OF EPHRIN-EPH SIGNALLING IN THE FORMATION PHASE OF BONE REMODELLING

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/620200

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Bone is constantly being renewed through bone remodelling. An amount of bone is removed by osteoclasts, and bone-forming osteoblasts make just enough to fill the space. We discovered that proteins known as ephrins are produced by osteoblasts, and act on neighbouring osteoblasts to help them make new bone. We aim to define how ephrins increase bone formation in remodelling, how that is controlled and how it might be used to find ways to increase bone formation.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $538,459.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

PTH and PTHrP | bone remodelling | bone structure | ephrins | osteoarthritis | osteoblast | osteoporosis

Related Links