Red cell disorders and the regulation of iron homeostasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/613688

Funding Status
Closed

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Funded Activity Summary

Iron is an essential nutrient, but it is also toxic when present in excess, so the amount of iron moving into and around the body must be tightly controlled. In this project we will investigate how this body iron movement is regulated, and in particular the role played by macrophages, the cells that clean up old red blood cells. An understanding of this process will be of great benefit in the analysis and treatment of important blood diseases and disorders of iron metabolism.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $605,096.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

haemolytic anaemia | hepcidin | hereditary spherocytosis | iron homeostasis | iron kinetics | iron overload | macrophage iron metabolism | thalassaemia

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