Functional Analysis of Novel Scabies Mite Serpins

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/613626

Funding Status
Closed

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Funded Activity Summary

Scabies is caused by microscopic mites burrowing through the skin, causing intense itching and providing prime breeding sites for bacteria. The resulting skin sores are very common among Aboriginal children in Australia leading to extreme levels of rheumatic fever-heart disease and renal failure in Indigenous communities. We have discovered mite products termed Serpins which interfere with the patients defence against the mites and the bacteria and aim to develop therapeutics.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $333,419.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Aboriginal Health | Host pathogen interactions | Inhibition of human complement system | Scabies mite infection of human epidermis | Serine protease inhibitors (Serpins) | bacterial skin infections (GAS, Staphylococcus) | crusted scabies | reuhmatic fever and heart disease, glomerulonephritis | scabies

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