Novel roles for IL-33 in the maintenance of bone mass and as a locally derived anabolic factor for bone

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/611805

Funding Status
Closed

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Funded Activity Summary

Over 10% of the population have thin, brittle bones that fracture easily, and is often seen in elderly people. When diagnosed, a fracture has usually already occurred and the bone is already thin. Drugs are available to stop further bone weakening, but building new bone would be best. We have found a protein in bone that reduces bone loss and stimulates bone formation processes. This project seeks to determine how this protein works and how to exploit it to design new bone building therapies.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $592,574.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Orthopaedics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bone | Cell differentiation | Chronic inflammation | Musculoskeletal | Osteoblast | Osteogenesis | Osteoporosis | Rheumatoid arthritis

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