Migratory cells to ganglionated network: self-organization of the enteric nervous system

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/607379

Funding Status
Closed

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Funded Activity Summary

The intestine has its own nervous system. This develops from cells that wander into the intestine during early development and self-organize to form the functional nervous system . The correct organization of the cells of this nervous system is required for correct intestine function. How they self-organize is not known, and there are diseases in which the process is disturbed. Molecular and cell biology and mathematical modelling will be used to understand how this occurs.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $328,294.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Hirschsprung's disease | cell adhesion | computer simulation | dysmorphogenesis | enteric nervous system | intestinal motility disorder | mathematical modelling | nervous system development | neural crest | neural crest cell lineage

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