Regulation of immune and inflammatory responses by short chain fatty acids and GPR43

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606952

Funding Status
Closed

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Funded Activity Summary

Innate immune mechanisms provide essential signals that determine the outcome of immune responses. The identity of these innate mechanisms may provide opportunities for manipulating immune responses, or controlling inflammatory responses. This proposal centers around a new and little-studied receptor, GPR43, which binds products of bacterial metabolism. This molecular pathway may explain how diet affect immune responses.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $549,092.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Asthma | Immune Regulation | Infectious Disease | Inflammatory Bowel Disease | Inflammatory Disease | Innate Immunity | Rheumatoid Arthritis

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