Immunoregulation in the Pathogenesis and Therapy of Autoimmune anti Myeloperoxidase Glomerulonephritis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606684

Funding Status
Closed

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Funded Activity Summary

Glomerulonephritis (GN) is a major health burden and crescentic GN is the most severe form. Most patients have autoantibodies to their own white blood cell ANCA, causing the disease. This study will use a mouse model of ANCA associated autoimmunity causing crescentic GN to define the normal mechanisms preventing the development of this disease (immunoregulation) and test the potential of new cell based therapies to prevent and treat the disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $283,880.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

CD4 cells | Crescentic Nephritis | Glomerulonephritis | Renal failure | Vasculitis | autoimmunity | glomerulonephritis | immunoregulation | myeloperoxidase

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