Renal AT2R are a therapeutic target for the treatment of hypertension in women

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606652

Funding Status
Closed

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Funded Activity Summary

Being female is associated with better renal function, resistenace to renal injury and hypertension, but it is not understood why. Our work demonstrates that women have more angiotensin type 2 receptors (AT2R) in the kidney then men. In men AT2R have been suggested to protect against hypertension and renal damage. We predict that the effects of AT2R stimulation will be greater in women and therefore the protective benefits greater.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $605,939.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cardiovascular disease | Hypertension | Kidney disease | blood pressure regulation | hypertension | pressure natriuresis | renal function | renin-angiotensin system

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