Role of the inositol polyphosphate 4-phosphatase type 2 in human breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606621

Funding Status
Closed

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Funded Activity Summary

Breast cancer is the most invasive cancer in females, affecting 1 in 9 women before the age of 85. Normally cells only divide when they receive a stimulus from a hormone or growth factor. The PI3K pathway responds to these stimuli and has been implicated in cancer when cells divide uncontrollably and invade surrounding tissue. We have identified a potential cancer suppressing gene, 4-ptase-2 that turns off the PI3K growth signals. We aim to characterize the role of 4-ptase-2 in breast cancer.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $611,032.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Breast cancer | PI3-kinase | breast cancer | estrogen resistance | estrogen responsive tumours | metastasis | prognostic marker | tumour spread | tumour staging | tumour suppressor

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