Hypoxia is the common pathway to renal failure

Funding Activity

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Funded Activity Summary

A lack of oxygen in the kidney (hypoxia) is a primary cause of kidney disease, but the mechanisms are not clear. To determine the processes involved, we will take a new approach; combining a mathematical model with studies of kidney oxygen regulation in both normal and diseased kidneys. We will determine the causes of hypoxia in kidney disease, and find out if preventing hypoxia has the potential to be a treatment for kidney disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $495,362.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

circulatory physiology of the kidney | ischemia-reperfusion injury | mathematical modelling | oxidative stress | oxygen consumption | polycystic kidney disease | renal failure | stereology | tissue oxygenation