Targeting polymyxin-resistant Gram-negative superbugs: development of novel antimicrobial lipopeptides

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606573

Funding Status
Closed

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Funded Activity Summary

Prevalence of resistance to antibiotics among Gram-negative 'superbugs' is a major global medical challenge, which is highlighted by the Bad Bugs, No Drugs campaign of the Infectious Diseases Society of America. There are virtually no new antibiotics in the current drug development pipeline for these dangerous pathogens. In this project, novel lipopeptides will be designed, synthesised and evaluated against these 'superbugs'. Information obtained will be crucial for further drug development.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $661,069.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmaceutical Sciences

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Development of novel antibiotics | Discovery and development of novel antibiotics | Infectious diseases | Multidrug-resistance to antibiotics | Multidrug-resistant Gram-negative bacterial infections | Pharmacological evaluations | Rational design and synthesis of antibacterial lipopeptides

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