Identifying a novel role for pigment epithelium-derived factor in obesity-related metabolic dysfunction

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606561

Funding Status
Closed

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Funded Activity Summary

Obesity is an important factor contributing to insulin resistance and type 2 diabetes; however, the factors linking these disorders are not well defined. A protein called PEDF is elevated in obesity and type 2 diabetes. This project will examine how PEDF causes insulin resistance and whether blocking PEDF's actions prevents insulin resistance. Successful completion of this project may lead to therapeutics that reduce the risk of developing type 2 diabetes.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $361,637.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipose tissue | endocrine factors | insulin resistance | lipid disorders | lipid metabolism | obesity-metabolism | skeletal muscle

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