The pathogenesis of infections caused by Clostridium sordellii.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606514

Funding Status
Closed

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Funded Activity Summary

The bacterium Clostridium sordellii causes necrosis and multiorgan failure with a very high mortality rate of 70% in infections of drug users, transplant and post-abortion patients, and 100% for post-partum patients. Little is known about how C. sordellii causes such devastating disease; treatment of these infections is currently ineffective. This project will make a major contribution to our understanding of how disease is caused and may lead to improved prevention and treatment stratetegies.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $400,232.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacterial Pathogenesis | Bacterial Toxins | Bacterial virulence mechanisms | Clostridium sordellii | Injecting drug user Clostridium sordellii infection | Microbial Genetics | Necrotic fasciitis | Post-abortive and post-partum Clostridium sordellii infection | Transplant infection

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