Role of human amnion epithelial cells in resolving hepatic fibrosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/606473

Funding Status
Closed

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Funded Activity Summary

When the liver is injured repeatedly by viruses and alcohol, it responds through a wound healing process that can lead to extensive scar tissue in the liver (cirrhosis). This condition may require liver transplantation and lifelong use of drugs to prevent the body from rejecting the new organ. To develop an alternate therapy, we will study if substances secreted by amnion cells from the human placenta (afterbirth), which would normally be discarded, can reduce liver scar tissue in mice .

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $618,755.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Kupffer cells | chronic liver injury | cirrhosis | hepatic fibrosis | hepatic stellate cell | hepatocyte | liver fibrosis | stem cell therapy | stem cell transplantation | stem cells

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