Exploring the mechanisms of generation of intestinal TH17 responses and the mechanisms of TH17 mediated pathology

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/604304

Funding Status
Closed

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Funded Activity Summary

Our research recently described a mouse that shows excellent similarities to human inflammatory bowel diseases. We further show that the disease mediating substances called cytokines are also similar between our mouse and UC. Particularly, a recently described network of cytokines that are the major mediators of disease in our mice and human IBD. This project examines how we can best interfere with the actions of these cytokines to treat and prevent intestinal inflammation.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $617,531.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Crohn's disease | Gut immunity | Inflammatory bowel disease | T cell immunity | autoimmunity | chronic inflammatory disease | cytokines and chemokines | intestine | mucosal inflammation | ulcerative colitis

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