Tetraspanins serve as molecular facilitators to regulate platelet thrombus formation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/603812

Funding Status
Closed

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Funded Activity Summary

Platelets are small fragments of megakaryocytes that circulate in the blood stream. They play an important role in preventing excessive blood loss at sites of tissue injury by sticking together and forming a haemostatic plug. Excessive platelet clumping in diseased blood vessels can lead to blockages and cause thrombotic diseases such as heart attack and stroke. We have discovered that tetraspanins serve to regulate platelet glycoproteins including integrin alphaIIbbeta, P2Y12 and thrombosis.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $589,544.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cardiovascular disease | Cerebral ischaemic stroke | Haemostasis | Patholgoy | Thrombosis | integrins and platelet glycoproteins including P2Y12 | platelet adhesion | signaling molecules | tetraspanins | thrombus formation

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