Molecular studies of the astrocyte reservoir of HIV-1 in the central nervous system

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/603708

Funding Status
Closed

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Funded Activity Summary

HIV infects the brain causing dementia in 10-20% patients. Strategies aimed at eradicating HIV infection fail to take into account CNS infection. Understanding the way in which HIV enters, infects and replicates in the brain is pivotal in development of drugs to prevent brain infection and dementia. Our studies have shown that HIV infection of the brain involves mechanisms distinct to those observed for blood and other organs. This study seeks to clarify such mechanisms.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $592,661.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

AIDS and immunodeficiency | Astrocytes | HIV-AIDS | Infectious disease | Mechanism of human immunodeficiency virus infection | Neuropathogenesis | Virus entry and replication | transcription

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