Glycan specificity and dependence in rotavirus host cell invasion

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/597439

Funding Status
Closed

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Funded Activity Summary

Rotavirus is a global pathogen that causes acute gastroenteritis resulting in dehydration and high levels of infant mortality. Annually, infections cause 138 million cases of infantile gastroenteritis and an estimated average of 600,000 deaths. Within Australia ~10,000 children under 5 yrs old are admitted to hospital annually with severe rotavirus-induced diarrhoea. This project will investigate the role of carbohydrates in rotavirus infection to help design new vaccines and inhibitors.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $636,602.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Carbohydrates | NMR spectroscopy | Protein Structure | Rotavirus infection | X-ray crystallography | anti-viral drug | infantile diarrhoea | roatvirus vaccine | rotaviral infection may be a trigger of type 1 diabetes

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