The role of linked cytokines in T helper cell differentiation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/596836

Funding Status
Closed

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Funded Activity Summary

An important class of T cells known as T Follicular Helper cells (TFH) orchestrate the immune response so that we can produce antibodies to fight infection. The novel finding that our Lab made last year is that the molecule interleukin 21 (IL-21) is a growth factor for TFH. The findings we have made thus far could be used in a number of ways. For eg, IL-21could be used to expand numbers of TFH, using them to boost vaccination or natural defences against viruses, bacteria and tumour cells.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $390,504.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Germinal center | Improving vaccination efficacy | Lupus (SLE) | Lymphoma | T follicular Helper cell | Th cell differentiation | costimulation | cytokine

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