Regulation of T follicular helper cell development and effector function in health and disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/596813

Funding Status
Closed

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Funded Activity Summary

Immune cells mature into distinct populations with specialized functions. One subsets are T follicular helper (TFH) cells which are important for instructing B cells to produce antibodies following infection or vaccination. The means by which TFH cells are generated are unknown. We will determine mechanisms whereby TFH cells are produced and how they function. We hope to design approaches that will modulate the function of TFH cells in cases of immunodeficiencies, autoimmunity or vaccination.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $419,197.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell-B cell interactions | autoimmune disease | cellular immunology | cytokines | effector CD4 T cells | humoral immunology | immune cell signalling | immune regulation | immunodeficiencies | immunodeficiency

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