Molecular memory: how DNA methylation contributes to spatial memory

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/585442

Funding Status
Closed

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Funded Activity Summary

The brain stores memories that can last a lifetime and our memory is core to mental health, but we still do not know how memories are stored. Here we explore a radical new theory that memory storage involves chemical modification of the DNA molecule - DNA-methylation. We will examine how memory changes patterns of DNA-methylation, and how modifying DNA-methylation can change memory. Our work will examine the biochemical basis of memory, and will inspire new strategies to treat memory disorders.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $482,842.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | dementia | epigenetics | gene expression | genomics | memory | memory disorders | mental health and aging | post traumatic stress disorder | synaptic plasticity

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