The Bidirectional Liver TRAIL

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/585414

Funding Status
Closed

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Funded Activity Summary

Liver damage after liver surgery or shock is called ischemia-reperfusion injury (IRI). Recovery after surgical removal of liver tissue is due to liver regeneration. IRI and liver regeneration are controlled by specialised proteins called cytokines, one of which, TRAIL, is essential for both IRI and liver regeneration. This research is to find out how TRAIL exerts such seemingly opposite effects. The aim is to learn how to protect the liver against damage, and to stimulate its recovery.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $424,262.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Nuclear factor-kappaB | TNF superfamily cytokines and receptors | alcoholic liver disease | cirrhosis | cytokines and liver disease | ischemia-reperfusion injury | liver regeneration | liver surgery | liver tumors | shock

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