Cellular and molecular determinants of preleukaemic and leukaemic stem cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/575590

Funding Status
Closed

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Funded Activity Summary

It has recently become evident that the formation, growth and relapse of many cancers is driven by a rare population of cancer stem cells (CSCs) that have the unique ability to propagate new tumours and are highly resistant to current therapies. However, which normal cells are transformed into CSCs is not known. We will take a potent cancer gene found in leukaemia, and switch it on and off in specific blood cells in mice to determine which healthy cells can be turned into leukaemic stem cells.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: Early Career Fellowships

Funding Amount: $292,635.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Animal Model | Carcinogenesis | Leukaemia | Oncogene

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