The role of the Hedgehog signaling pathway in asbestos associated malignant mesothelioma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/572676

Funding Status
Closed

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Funded Activity Summary

Mesothelioma is a aggressive asbestos related cancer mainly of the lung with no effective treatment. Evidence is pointing to the reactivation and aberrant expression of developmental signalling pathways such as the hedgehog signalling pathway as critical to the pathogenesis of certain types of cancer. This study will determine if mesothelioma is regulated by signalling through the hedgehog pathway and by blocking this pathway we will attempt to inhibit tumour growth.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $563,554.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Animal model | Asbestos-related diseases | Cell signalling | Inhibition of cancer cell growth | Mesothelioma | Pharmacological intervention | Respiratory diseases | Respiratory diseases and sciences | Signalling pathways

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