Regulation of liver iron loading in hereditary haemochromatosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/572601

Funding Status
Closed

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Funded Activity Summary

Hereditary haemochromatosis is a common iron overload disorder. It affects 1 in 200 Australians causing liver iron overload, fibrosis, cirrhosis and cancer. The severity of liver iron overload in haemochromatosis is variable. In this study we will determine whether factors that are known to regulate iron metabolism such as iron levels, oxidative stress and inflammation modify liver iron transport systems and the degree of liver iron loading in animal models of haemochromatosis.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $663,188.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Hereditary haemochromatosis | alcoholic liver disease | hereditary haemochomatosis | inflammation | iron metabolism | iron overload | liver | liver disease | oxidative stress

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