Randomised trial of homocysteine lowering treatment of depression in later life (B-VITAge)

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/572594

Funding Status
Closed

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Funded Activity Summary

The causes of depression in later life are varied and complex, but available evidence suggests that cardiovascular disease plays an important role. High homocysteine (a robust risk factor for myocardial infarction and strokes) accounts for about 20% of all cases of depression in older age. We have previously shown that treatment with vitamins B12, B6 and folate reduces homocysteine. We propose to run a trial to test if lowering homocysteine decreases the severity and prevalence of depression.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $775,530.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

depression | depression, depressive episode, depressive disorders | folate | geriatrics and gerontology | homocysteine | homocysteine lowering treatment | randomised trial | randomised, placebo-controlled clinical trial | vitamin B12

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