Ontogeny of Toll (TLR) function in normal and allergic children: the impact of microbial-rich environments

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/572501

Funding Status
Closed

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Funded Activity Summary

Reduced exposure to bacteria during early life has become a leading candidate to explain the escalating rate of allergic disease. Despite this, the development and maturation of the pathways involved in normal recognition of bacteria in children has not been explored. In this proposal we set out to address this critical shortcoming in both normal and allergic children. Mapping normal maturation of such pathways will help us to identify better early markers of allergic disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: Career Development Fellowships

Funding Amount: $387,489.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Anaesthesiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Allergic diseases and atopy | Allergy | Early childhood | Immune development | Innate immunity

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