Factor XII dependent coagulation, thrombin and platelet glycoprotein 1ba in arterial thrombosis and bleeding disorders

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/571265

Funding Status
Closed

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Funded Activity Summary

Clot formation is the key event underlying heart attacks and strokes. There is new data that Factor XII (FXII) can play an important role in clot formation-thrombosis. We aim to examine the role FXII plays in clot formation, in particular the role of FXII in thrombin generation, which is the central event of clot formation, and its interaction with platelet glycoprotein 1ba (another important molecule in thrombosis). New insights into clotting and new therapies can result from our research.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $104,664.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Coagulation activation | Coagulation factor deficiency | Contact factors | Platelet activation | Thrombin generation

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