Signalling and transcriptional activity for craniofacial morphogenesis in an experimental genetic mouse model

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/571210

Funding Status
Closed

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Funded Activity Summary

Abnormalities in craniofacial development affect 2-1000 births in Australia. The aim of this project is to identify genes crucial for the development of the head and face. In particular the project focuses on the Twist1 gene. TWIST1 plays a key role in craniofacial development and individuals lacking functional Twist1display facial anomalies such as craniosynostosis and cleft palate. Dissecting the function of Twist1 is essential to identifying new avenues for the prevention of these defects.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $74,755.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cre-lox knockout mice and Twist1 | abnormal embryogenesis and birth defects | craniofacial development and craniosynostosis | developmental genetics | signalling pathways and transcriptional regulation

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