Development of dynamin inhibitors as novel therapies for epilepsy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/571076

Funding Status
Closed

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Funded Activity Summary

Epilepsy affects 1% of people, but 30% do not respond to current anti-epileptic drugs (AEDs). Traditional drug discovery has not improved this situation. Our team discovered two exciting new targets for design of better AEDs. One of them blocks seizure in animals. Our aim is to determine how well they work in true animal models of epilepsy. If successful, this will accelerate development of new AEDs with less side-effects, benefiting large sectors of the Australian community.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $903,376.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry and metabolomics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Anti-Convulsant | Anti-epileptic drugs | Dynamin | Epilepsy | Neuronal burst firing | New epilepsy treatments | Pharmacodynamics | True models of epilepsy

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