Mechanisms of disease in bacterial meningitis

Funding Activity

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Funded Activity Summary

Some bacteria can cause inflammation of the brain (bacterial meningitis). This leads to 170,000 deaths annually in the world. Many patients who survive after antibiotic treatment have lifelong disabilities like deafness, and problems of memory and learning. We aim to show that a certain biochemical pathway in the brain contributes to death and disability, with a view to identifying new drug treatments that can be used alongside antibiotics to improve disease outcomes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $471,483.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial infection | bacterial meningitis | blood-brain barrier | cytokine | immunopathology | infectious disease | kynurenine pathway | meningitis | neuronal injury