The role of calcium and TRPC channels in sinoatrial node ageing

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570926

Funding Status
Closed

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Funded Activity Summary

The failure of pacemaker function is a common clinical problem in the elderly who become more susceptible to cardiac arrhythmias. We recently discovered a new calcium channel called the transient receptor potential canonical channel (TRPC) in the pacemaker cells. The aim of this research is to study the role of TRPC channels in pacemaker ageing. Improved understanding of the mechanisms of the pacemaker ageing may provide new therapeutic strategies for reducing the risk of cardiac arrhythmias.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $385,301.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Arrhythmias | Heart rate | Sick sinus syndrome | Sinoatrial node | Store-operated Ca channels | TRPC | ageing | intracellular Calcium

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