The anti-inflammatory role of collagen IV in asthma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570867

Funding Status
Closed

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Funded Activity Summary

We have discovered that a protein, tumstatin, is missing from the lungs of people with asthma. We now have exciting data showing, for the first time, that tumstatin can stop inflammation. If tumstatin is part of the system that normally limits inflammation in the lungs its absence in asthma may be critical. In this grant we will discover how tumstatin works to block inflammation and why it is absent in asthma. Our studies will provide vital information about the role of tumstatin in the airways.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $317,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway hyperresponsiveness | asthma | extracellular matrix | inflammation | mesenchymal cells | pro and anti-inflammatory factors

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