Molecular basis of Fluoroquinolone resistance

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570784

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Bacterial antibiotic resistance is mediated through specific biological molecules, so-called multidrug transporter proteins, which effectively export drugs from the cell. This proposal aims to solve the 3D structure of a multidrug resistance protein, NorM, which confers resistance to fluoroquinolone type drugs. Through this, we will provide detail into transport across the membrane of cells, and thus present a molecular understanding of bacterial antibiotic resistance.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $542,521.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biophysics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Antibiotic resistance | Bacterial pathogenes | Membrane protein | Membrane transport | Multidrug resistance | Pathogenic mechanisms | Protein structure | X-ray crystllography

Related Links