Real-time visualisation of dendritic cell responses during cutaneous Leishmania infection

Funding Activity

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Funded Activity Summary

Leishmaniasis is one of the six major tropical diseases identified by the WHO for intense further study. The disease affects millions of people worldwide demanding the development of improved vaccines. A prerequisite is a better understanding of the basic mechanisms of anti-parasite immunity. This proposal will employ a novel approach, intravital two-photon microscopy, to directly visualise Leishmania parasites and immune cells in the skin in order to decipher anti-Leishmania immunity.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $511,294.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell migration | cell-cell communication | dendritic cells and macrophages | dermatology | functional imaging | immunity to infection | infectious disease | microenvironment | parasitology | skin infections