Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570768

Funding Status
Closed

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Funded Activity Summary

Two million people die from tuberculosis (TB) each year. The immune system is unable to eradicate the TB bacterium, and the type of immune response needed to protect against the disease is poorly understood. We will use animal models of TB infection and sophisticated immunological techniques to decipher how the TB bacterium interacts with the immune sytem and causes disease. We will also develop new TB vaccines that aim to boost the immune response in the lung, the main site of TB infection.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $547,970.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Dendritic cells | Immune response | Mycobacterial infection | Tuberculosis | Vaccine development | disease model, animals | immunity to infection | improvement of vaccine efficacy

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