The role of dysferlin in muscular dystrophy and skeletal muscle membrane repair.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570744

Funding Status
Closed

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Funded Activity Summary

Patients who lack the protein dysferlin have muscular dystrophy. These patients are unable to repair their muscle membranes, which get damaged during normal activities. A defect in membrane repair is a new pathway implicated in the muscular dystrophies, and it is likely that other patients will also have defective muscle membrane repair. We will find out how dysferlin mediates its role in membrane repair, and identify other dysferlin-interacting proteins, as these may also underlie disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $316,667.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology And Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Membrane trafficking | Molecular genetics | Muscular dystrophy | Neurogenetics | muscle degeneration | muscular dystrophy | protein trafficking

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