Role in disease and vaccine potential of cell surface o-linked glycoproteins in pathogenic Neisseria.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569737

Funding Status
Closed

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Funded Activity Summary

Bacteria that have adapted to life exclusively in the human host have developed unique strategies to colonize the host and to evade the immune response. An emerging strategy is modification of bacterial surface proteins with sugars or other modifications. Our data suggests a key role for these modifications in disease. We will investigate how the modifications are made, discover structures of novel modifications and determine their precise role in disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $212,347.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Gonorrhea | Meningitis | Meningococcal Disease | Neisseria gonorrhoeae | Neisseria meningitis | Septicaemia | glycobiology

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