Molecular mechanisms that help organise effective synaptic transmission.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569680

Funding Status
Closed

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Funded Activity Summary

This study will test the idea that adhesion molecules alpha4- and beta2-laminin are needed for proper development and function of motor nerve - muscle connections. This study will provide insights into how such molecules control effective nerve-muscle communication, in both health and disease. We also believe that our results will provide the basic knowledge needed for identifying pharmacological targets that could improve such connections, and to promote reconnections between nerve and muscle.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $555,825.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium channels | molecular neuroscience | motor neuron disease | muscle function deficits - loss of motor control | muscular dystrophy | nerve terminals | neuromuscular diseases | neuromuscular junction | sarcopenia | synaptic transmission

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