A comprehensive analysis of Myb target genes involved in myelopoiesis and myeloid transformation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569639

Funding Status
Closed

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Funded Activity Summary

The MYB gene is essential for both normal blood cell formation and the growth of leukaemia cells. It acts by switching other genes (target genes) on and off. This project aims to advance our understanding of how MYB functions, by carrying out a comprehensive search for MYB target genes. In particular it will focus on target genes that help explain MYB's ability to control cellular growth and maturation. Some of these target genes may provide leads for future anti-cancer drug development.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $511,294.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Myb oncogene | breast cancer | colon cancer | gene regulation | leukaemia | micro RNA | microarray | myelopoiesis

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