Neogenin regulates progenitor division and interneuron migration in the developing forebrain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569638

Funding Status
Closed

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Funded Activity Summary

In humans, mutations in genes controlling the production of new neurons in the embryonic brain result in severe disruption of the adult cortex. This project tests the hypothesis that one cell surface molecule, Neogenin, regulates the birth of new neurons and their subsequent travels through the developing brain to form the neocortex. The outcome of these studies will provide fundamental insights into the aberrant processes that underlie human mental retardation, epilepsy, dyslexia and autism.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $526,878.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brain development | cell division | cell signalling | developmental neurobiology | mental retardation | molecular neuroscience | neural migration | neurogenesis | neuron pathfinding-fasciculation

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