Protease Activated Receptor 2 : A New Drug Target For Inflammatory Diseases and Cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569595

Funding Status
Closed

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Funded Activity Summary

A new class of proteins (Protease Activated Receptors) has been found on the surfaces of many different types of cells. They are believed to be natural sensors that respond to traces of degradative enzymes called proteases. This project will create and evaluate new drugs for one of these receptors thought to regulate inflammatory diseases (e.g. arthritis, inflammatory bowel disease, asthma, pancreatitis) and cancers, while providing a better understanding of a new mechanism of immune defence.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $739,434.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry and metabolomics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Agonist and Antagonist | Molecular pharmacology | Peptide mimics | Protease Activated Receptor | Proteins and Enzymes | arthritis | cancers | inflammatory diseases

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