Correlative structure-function studies of cis- and trans-Golgi membrane traffic in mammalian cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/569535

Funding Status
Closed

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Funded Activity Summary

This project combines imaging by light and electron microscopy with additional techniques for studying protein function at the molecular level, to elucidate how changes in the 3D organisation of cellular machinery can lead to fundamental changes in the function and health of mammalian cells. Although this work includes detailed investigation of the 'insulin factory', it has the potential to modify established concepts on membrane traffic and protein secretion well beyond the field of diabetes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $649,531.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | electron microscopy | insulin secretion | membrane transport | mis-targeting of proteins to organelles | protein trafficking | type 1 diabetes | type 2 diabetes

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