Antibody-directed delivery of anti-restenotic agents using inorganic nanoparticles

Funding Activity

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Funded Activity Summary

Arteries that have been surgically treated to remove fatty lesions that block blood flow frequently become re-blocked (restenosed), and drugs to prevent this re-blockage often have bad side-effects. We propose to prevent these complications by target-delivering the drugs directly and only to the required site using a single injection at the time of surgery. This will limit systemic side-effects, treatment costs and incidence of reblocking and bleeding complications.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $327,151.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-restenosis therapy | atherosclerosis | cardiovascular disease | drug delivery | drug delivery systems | drug targeting | nanotechnology | restenosis | restenosis after angioplasty | targeted therapy