Identification and characterisation of phosphorylation events taking place during human sperm capacitation

Funding Activity

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Funded Activity Summary

Male infertility affects one in every twenty Australian males and one third of all infertile couples worldwide. The most common cause of human infertility is not a failure to produce sperm, but a failure of these cells to express a normal capacity for fertilization. The cause of this loss of functional competence is unclear. We are going to use our technical expertise in proteomics to characterize the molecular pathways responsible for the defective sperm function seen in infertile patients.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $280,400.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Hyperactivation | Idiopathic infertility | Immature sperm maturation | Male infertility | Nano-flow LC-MS-MS | Phosphoproteomics | Sperm Capacitation | Sperm motility defects | Tyrosine phosphorylation | pp60c-SRC