Hypoxia-inducible factor-1 (HIF-1): Pharmacological and molecular insights into its role in brain protection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/568769

Funding Status
Closed

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Funded Activity Summary

At present, there are no effective therapies for reducing brain damage which can occur after acute brain insults including birth asphyxia. This project aims to study whether increasing a naturally occurring protective protein (HIF) in the brain can minimize brain damage in a model of perinatal brain injury. We plan to validate HIF as a novel therapeutic target for reduce brain injury and promote brain repair processes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $293,229.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry and metabolomics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Animal Models | Cell Culture | Cerebral Ischemia | HIF-1 | Hypoxia | Neonatal Brain Injury | Tolerance

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