The role of the TGF-b superfamily cytokine MIC-1 in prostate cancer pathogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/568762

Funding Status
Closed

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Funded Activity Summary

We have discovered that a protein called MIC-1 is strongly linked to prostate cancer and is made in large amounts by this tumor. There is a lot of circumstantial evidence that it is involved in the prostate cancer but the proof is missing. We propose to breed mice that are both prostate cancer prone and have genetically modified MIC-1 : mice either are unable to make MIC-1 , or make it in large amounts. We will determine how MIC-1 affects prostate cancer development.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $579,138.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

MIC-1 | animal model of cancer | cancer biology | cytokine | metastatsis | pathogenesis | prostate cancer

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