The distinctive roles of tissue transglutaminase isoforms in neuroblastoma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/568753

Funding Status
Closed

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Funded Activity Summary

Neuroblastoma is the commonest solid tumour in early childhood. Neuroblastoma caused by N-Myc oncogene accounts for about one third of the disease and represents a more aggressive subtype with a worse clinical outcome. This project aims to identify factors responsible for N-Myc-induced neuroblastoma initiation and factors sensitizing neuroblastoma cells to anti-cancer drugs, and to provide the basis for clinical trials of a combination therapy in children with neuroblastoma.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $311,567.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer treatment | cell differentiation | histone deacetylase | histone deacetylase inhibitor | neuroblastoma | therapeutics | tumourigenesis

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